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Understanding MBC > What Is a PIK3CA Mutation?
The PIK3CA mutation is a type of biomarker. PIK3CA mutations are somatic mutations, which are not passed down from parent to child (not inherited). These are changes to the genes that give cells instructions about what to do and how often to grow and divide.1,2
DNA is found in all cells and is made up of a variety of different “genes.” Each gene is a set of instructions for making a different part of the cell. The PIK3CA gene gives instructions for part of the cell known as “PI3Kα” (PI3K-alpha).9,17